Development of a continuous assay for high throughput screening to identify inhibitors of the purine salvage pathway in Plasmodium falciparum
Malaria, an infectious disease caused by protozoan parasites from the genus Plasmodium, represents a serious global health threat.The continued emergence of drug resistant strains has severely decreased current antimalarial drug efficacy and led to a perpetual race for drug discovery.Most protozoan parasites, including Plasmodium spp., are unable t